Letters from two young Christian Onondaga Indians, Thomas La Fort and Jameson L. Thomas, about their efforts to get an education so they might help their tribe; from Chief David Hill, leader of the Christian Onondagas, asking for financial and political aid when the New York state legislature refused money for a school on the Onondaga reservation, and when the Christian and pagan Indians sought to divide the reservation between them.

With a covering letter from the author to Isaiah Thomas, 1793. The manuscript was published by Thomas at Worcester, 1794.

A Sachem and Civil War adjutant to Ulysses Grant, Ely Samuel Parker was an important figure in the Seneca Indian nation during the first half of the nineteenth century. Trained as an engineer, Parker was deeply involved in the Senecas' land disputes with the Ogden Land Company and he played an important role in interpreting Seneca culture for a white audience, most notably as a consultant for Lewis Henry Morgan. Collected by Arthur C. Parker, the Ely Samuel Parker Papers include correspondence, manuscripts, and printed materials relating primarily to Seneca affairs, history, language, and culture, as well as politics, education, engineering, and the Civil War. Among Parker's correspondents were Henry Clay, Millard Fillmore, Henry M. Flagler, Lewis Henry Morgan, Henry Rowe Schoolcraft, Daniel Webster, and Asher Wright. Several letters relate to Parker's service as engineer of public buildings in Galena, Illinois, and to his Masonic activities. Among the noteworthy items in the collection are several essays on Seneca history and culture, a fragment of Parker's diary, 1847, and a significant quantity of material on the Seneca language assembled by Asher Wright.

Robert Maskell Patterson (1787-1854, APS 1809) was a professor of chemistry and natural philosophy at the University of Pennsylvania (1812-1828) and professor of natural philosophy at the University of Virginia (1828-1835). He was director of the U.S. Mint from 1835 to 1851. His father, Robert Patterson, was a revolutionary soldier, professor of mathematics at the University of Pennsylvania (1779-1814), and director of the U.S. Mint (1805-1824).

Founded in 1743 by Benjamin Franklin, the American Philosophical Society was the first learned society in the United States. For over 250 years, the Society has played an important role in American cultural and intellectual life. Until the mid-nineteenth century, the Society fulfilled the role of a national academy of science, national library and museum, and even patent office. Early members of the Society included Thomas Jefferson, David Rittenhouse, Benjamin Rush, Stephen Peter Du Ponceau, George Washington, and many other figures prominent in American history. The Archives of the American Philosophical Society consists of 192.25 linear feet of material, organized into thirteen record groups dating back to 1743. The Society's archives extensively documents not only the organization's historical development but also its role in American history and the history of science and technology.

A physician, natural historian, and professor at the University of Pennsylvania, Benjamin Smith Barton (1766-1815) was one of the central figures in Philadelphia's early national scientific establishment. Having received his medical training in European universities, Barton was appointed Professor at the University of Pennsylvania in 1789, lecturing on botany, materia medica, natural history. A prolific author, he established his reputation as one of the nation's preeminent botanists through his botanical text book The Elements of Botany (1803), but his contribtions to zoology, ethnology, and medicine were equally noteworthy. Barton's monograph on the "fascinating faculty" of the rattlesnake and his efforts in historical linguistics (New Views of the Origin of the Tribes and Nations of America, 1798) were widely read, and his Philadelphia Medical and Physical Journal (1804-1809) was one of the nation's first medical journals and an important outlet for natural historical research. The Barton Papers offer a comprehensive view of the professional work of Benjamin Smith Barton from the time of his return to the United States in 1789 until his death. The collection is divided into five series: Correspondence, Subject Files, Bound Volumes, Graphic Materials, and Printing Plates. The collection includes a particularly valuable series of botanical, medical, and natural historical drawings collected by Barton for research, reference, and publication. Among the many artists represented are William Bartram, Frederick Pursh, Pierre Turpin, and Benjamin Henry Latrobe.